Influence of Poly(L-Lactic Acid) Nanofibers and BMP-2–Containing Poly(L-Lactic Acid) Nanofibers on Growth and Osteogenic Differentiation of Human Mesenchymal Stem Cells

The effect of electrospun poly(lactic acid) and nanohydroxyapatite nanofibers’ diameter on proliferation and differentiation of mesenchymal stem cells

Objective(s): Electrospun nanofibrous mats of poly(lactic acid) (PLA) and nanohydroxyapatite (nano-HA) were prepared and proliferation and differentiation of mesenchymal stem cells on the prepared nanofibers were investigated in this study. Materials and Methods: PLA/nano-HA nanofibers were prepared by electrospinning. The effects of process parameters, such as nano-HA concentration, distance, ...

the effect of electrospun poly(lactic acid) and nanohydroxyapatite nanofibers’ diameter on proliferation and differentiation of mesenchymal stem cells

objective(s): electrospun nanofibrous mats of poly(lactic acid) (pla) and nanohydroxyapatite (nano-ha) were prepared and proliferation and differentiation of mesenchymal stem cells on the prepared nanofibers were investigated in this study. materials and methods: pla/nano-ha nanofibers were prepared by electrospinning. the effects of process parameters, such as nano-ha concentration, distance, ...

Differentiation of Human Mesenchymal Stem Cell into Chonderocyte Like Cells 3D Poly Lactic Acid Glycosaminoglycan (PCL-GAG) Nano Fibre Scaffold

Introduction: Failure of human body tissue and organs is believed to be one of the most important health problems all over the world. The great challenge for tissue engineers is to optimize suitable systems to separate, proliferate and differentiate the cells so that they can set out to create tissue by a harmonic 3-D growth. Therefore, the tissue engineers must provide an environment like the ...

Poly(lactic acid) (PLA) Nanofibers for Bone Tissue Engineering

Preparation and investigation of polylactic acid, calcium carbonate and polyvinylalcohol nanofibrous scaffolds for osteogenic differentiation of mesenchymal stem cells

Objective(s): In this study, the effect of electrospun fiber orientation on proliferation and differentiation of mesenchymal stem cells (MSCs) was evaluated. Materials and Methods: Aligned and random nanocomposite nanofibrous scaffolds were electrospun from polylactic acid (PLA), poly (vinyl alcohol) (PVA) and calcium carbonate nanoparticles (nCaP). The surface morphology of prepared nanofibrou...